Leucine 2,3-aminomutase, an enzyme of leucine catabolism.
نویسنده
چکیده
The initial step in the fermentation of leucine to acetate, isobutyrate, and ammonia by Clostridium sporogenes is the B12 coenzyme-dependent conversion of alpha-leucine to beta-leucine (3-amino-4-methylpentanoate). The amino group migration reaction, catalyzed by leucine 2,3-aminomutase, is reversible and is inhibited by intrinsic factor. The enzyme activity has been found in several clostridia, in rat, sheep, rhesus, and African green monkey livers, and in human leukocytes.
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ورودعنوان ژورنال:
- The Journal of biological chemistry
دوره 251 7 شماره
صفحات -
تاریخ انتشار 1976